Fmoc-L-Pro-OH

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Fmoc-L-Pro-OH (CAS No. 71989-31-6) is a widely used derivative of L-proline for Fmoc-based solid-phase peptide synthesis. Its cyclic structure plays a role in inducing turns and rigidity within peptide chains, making it a key component in the development of GLP-1 analogs such as Semaglutide and Tirzepatide. This compound offers high purity and predictable reactivity in automated synthesis workflows.

CAS No.: 71989-31-6
Molecular Formula: C₂₀H₁₉NO₄
Purity: 99% min

Appearance White to off-white crystalline powder
Molecular Weight 337.4 g/mol
Density 1.3 ± 0.1 g/cm³
Boiling Point 548.6 ± 43.0 °C at 760 mmHg
Melting Point 112–115 °C
Flash Point 285.6 ± 28.2 °C
Packaging 25 kg / fibre drum
Customs Code 29339980
Storage Conditions Keep sealed in a dry place away from heat and light to preserve structural integrity

Product Name
1. Fmoc-Pro-OH;
2. Fmoc-L-proline;
3. N-(9-Fluorenylmethoxycarbonyl)-L-proline;
4. Fmoc-L-Pro-OH;
5. N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-proline;
6. L-Proline-N-Fmoc;
7. (2S)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]pyrrolidine-2-carboxylic acid
Production Capacity 5 ton/month
Applications Raw material for GLP-1 peptide synthesis, polypeptides, Semaglutide, and Tirzepatide

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