Fmoc-L-Tyr(tBu)-OH

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Fmoc-L-Tyr(tBu)-OH (CAS No. 71989-38-3) is a protected tyrosine used in Fmoc-SPPS. It features an Fmoc group at the α-amino position and a tert-butyl group on the phenolic hydroxyl, which prevents undesired side reactions during synthesis. This derivative is commonly applied in the preparation of GLP-1 peptides such as Semaglutide and Tirzepatide.

CAS No.: 71989-38-3
Molecular Formula: C₂₈H₂₉NO₅
Purity: 99% min

Appearance White powder
Molecular Weight 459.5 g/mol
Density 1.3 ± 0.1 g/cm³
Boiling Point N/A
Melting Point 86–90 °C
Flash Point N/A
Packaging 25 kg / fibre drum
Customs Code 29242970
Storage Conditions Store at 2–8 °C in a sealed container protected from light and moisture

Product Name
1. Fmoc-Tyr(tBu)-OH;
2. Fmoc-O-tert-butyl-L-tyrosine;
3. Fmoc-L-Tyr(tBu)-OH;
4. Fmoc-Tyr(t-Bu)-OH;
5. (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(tert-butoxy)phenyl)propanoic acid;
6. N-Fmoc-O-tert-butyl-L-tyrosine;
7. Nalpha-Fmoc-O-tert-butyl-L-tyrosine
Production Capacity 3 ton/month
Applications Raw material for GLP-1 peptide synthesis, polypeptides, Semaglutide, and Tirzepatide

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