Fmoc-L-Thr(tBu)-OH

Fmoc-L-Thr(tBu)-OH
Fmoc-L-Thr(tBu)-OH
Fmoc-L-Thr(tBu)-OH
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Fmoc-L-Thr(tBu)-OH (CAS No. 71989-35-0), also known as N-Fmoc-O-tert-butyl-L-threonine, is a protected amino acid widely used in solid-phase peptide synthesis. It contains a Fmoc group shielding the α-amino function and a tert-butyl group protecting the hydroxyl side chain, allowing selective deprotection during synthesis. This compound plays a key role in assembling GLP-1 analogs such as Semaglutide and Tirzepatide. Offered as a white crystalline powder with 99% min purity, it has a molecular weight of 397.5 g/mol and formula C₁₈H₂₃NO₅. Proper storage at 2–8 °C in a sealed container is recommended to maintain stability.

  • CAS No.: 71989-35-0
  • Molecular Formula: C₁₈H₂₃NO₅
  • Purity: 99% min
  • Appearance White crystalline powder
  • Molecular Weight 397.5 g/mol
  • Density 1.2 ± 0.1 g/cm³
  • Boiling Point 581.7 ± 50.0 °C at 760 mmHg
  • Melting Point 131–134 °C
  • Flash Point 305.6 ± 30.1 °C
  • Packaging 25 kg / fibre drum
  • Storage Conditions Seal and store at 2–8 °C
  • Customs Code 29242990
  • Product Name
    1. Fmoc-Thr(tBu)-OH;
    2. Fmoc-O-tert-butyl-L-threonine;
    3. N-(9-Fluorenylmethoxycarbonyl)-O-tert-butyl-L-threonine;
    4. (2S,3R)-2-(((9-Fluorenylmethoxy)carbonyl)amino)-3-(tert-butoxy)butanoic acid
  • Production Capacity 3 ton/month
  • Applications Raw material for GLP-1 peptide synthesis, polypeptides, Semaglutide, and Tirzepatide
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