Microcarrier Bioreactor

Microcarrier Bioreactor
Microcarrier Bioreactor
Microcarrier Bioreactor
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Stainless Steel Tank & Vessel Manufacturing

Stainless steel reaction vessel for adherent cell culture

The unique design of RITAI microcarrier bioreactor allows the adherent cells to attach better to the microcarriers, resulting in increased productivity and significantly reduced costs. This bioreactor is suitable for the cultivation of adherent cells such as animal and plant cells. It adopts a modular design that can be customized according to your needs, providing functions such as online CIP (Cleaning-in-Place), SIP (Sterilization-in-Place), automatic lifting of tank covers, cold point monitoring in sterilization process, data storage, and remote monitoring.
The low shear force of this microcarrier bioreactor enables high-density and large-scale cell cultivation.

Specifications
Culture volume 1L to 5000L
Microcarrier concentration Up to 20g/L
Cell density 1.5 x 107cells/mL
Vessel material 316L SS
Surface finish Internal polishing 0.2-0.4μm
External polishing 0.8μm
Standard material 316L stainless steel (body)
304 stainless steel (jacket)
Design pressure 0.3MPa
Working pressure 0.25MPa
Roughness of surface in contact with materials Ra≤0.4
Interface Sight glass, side glass,light glass, feeding valve assembly connection, foam sensor pocket, pressure sensor pocket, sample cock, vent bottom valve, alkali adding connection, burst discs
Agitation method Bottom mounted magnetic drive agitator, PID control
Agitation speed 25~250rpm, ±1rpm
Industry served
  • Reaction cultivation systems for biolaboratories
  • Seed cultivation systems for agricultural products
  • Bioreaction systems for vaccine manufacturing companies
Application
  • Batch, fed-batch, or continuous perfusion cultivation of insect, plant, and mammalian cells.
  • Microcarrier cultivation of adherent cell, suspension cultivation of non-adherent cell.
  • Cell seed amplification.
  • Pilot-scale sample preparation and large-scale production of vaccines.
Cases

RITAI microcarrier bioreactor has been successfully used for cell culture of BHK/BSR, VERO, CHO, MDCK, 293, MARK145, PK15, and other cell lines.

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