18-(tert-Butoxy)-18-oxooctadecanoic acid

18-(tert-Butoxy)-18-oxooctadecanoic acid
18-(tert-Butoxy)-18-oxooctadecanoic acid
18-(tert-Butoxy)-18-oxooctadecanoic acid
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Used as a side chain component in peptide synthesis, 18-(tert-Butoxy)-18-oxooctadecanoic acid (CAS No. 843666-40-0, molecular formula C₂₂H₄₂O₄) is a white solid containing a tert-butyl ester group that increases its hydrophobicity. This property makes it especially useful in the development of lipid-modified peptides, where enhanced membrane interaction or prolonged half-life is desired. It’s widely used in the synthesis of GLP-1 receptor agonists such as Semaglutide and Tirzepatide, contributing to the design of stable, long-acting structures. The compound is packaged in 25 kg fiber drums and should be stored in sealed containers at room temperature, in a dry environment to preserve its integrity.

  • CAS No.: 843666-40-0
  • Molecular Formula: C₂₂H₄₂O₄
  • Purity: 99% min
  • Appearance White to white-like solid
  • Molecular Weight 370.6 g/mol
  • Density 0.950 ± 0.06 g/cm³ (predicted)
  • Boiling Point 470.7 ± 18.0 °C (predicted)
  • Melting Point 68 °C
  • Flash Point N/A
  • Packaging 25 kg/fibre drum
  • Customs Code 2917198090
  • Storage Conditions Store in a dry, sealed container at room temperature
  • Product Name
    1. 18-(tert-butoxy)-18-oxooctadecanoic acid;
    2. Octadecanedioic acid mono-tert-butyl ester;
    3. 18-[(2-methylpropan-2-yl)oxy]-18-oxooctadecanoic acid;
    4. Octadecanedioic Acid Mono(1,1-dimethylethyl) Ester
  • Monthly Production Capacity 500 kg/month
  • Applications Side chain intermediate for Semaglutide and Tirzepatide synthesis
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