Used in the synthesis of GLP-1 peptides and other pharmaceutical polypeptides, Fmoc-L-His(Trt)-OH (CAS No. 109425-51-6) is a histidine derivative with dual protection: an Fmoc group on the N-terminus and a trityl (Trt) group on the imidazole ring. This configuration prevents undesired side reactions during stepwise peptide assembly, especially under solid-phase conditions. The compound has a molecular weight of 619.7 g/mol and a molecular formula of C₄₀H₃₃N₃O₄. It is supplied as a white powder with 99% min purity and should be stored sealed at 2–8 °C to preserve its stability and reactivity throughout the synthesis process.
- CAS No.: 109425-51-6
- Molecular Formula: C₄₀H₃₃N₃O₄
- Purity: 99% min
