Fmoc-L-Cys(Trt)-OH

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Fmoc-L-Cys(Trt)-OH (CAS No. 103213-32-7) is a sulfur-containing amino acid derivative commonly used in Fmoc-SPPS protocols. The Fmoc group protects the α-amino group, while the Trt group shields the thiol side chain, minimizing oxidation during synthesis. Its use is especially relevant in constructing GLP-1 analogs, including Semaglutide and Tirzepatide.

CAS No.: 103213-32-7
Molecular Formula: C₃₇H₃₁NO₄S
Purity: 99% min

Appearance White powder
Molecular Weight 585.7 g/mol
Density 1.3 ± 0.1 g/cm³
Boiling Point 763.4 ± 60.0 °C at 760 mmHg
Melting Point 415.5 ± 32.9 °C
Flash Point 285.6 ± 28.2 °C
Packaging 25 kg / fibre drum
Customs Code 29309090
Storage Conditions Store at 2–8 °C in a dry, sealed container to avoid exposure to moisture and air

Product Name
1. Fmoc-Cys(Trt)-OH;
2. FMOC-S-trityl-L-cysteine;
3. N-Fmoc-S-trityl-L-cysteine;
4. (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-tritylsulfanylpropanoic acid;
5. N(alpha)-Fluorenylmethyloxycarbonyl-S-tritylcysteine;
6. L-Cysteine,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-
Production Capacity 3 ton/month
Applications Raw material for GLP-1 peptide synthesis, polypeptides, Semaglutide, and Tirzepatide

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