H-Thr(tBu)-OH

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O-tert-Butyl-L-threonine (H-Thr(tBu)-OH) is a protected form of L-threonine commonly used in solid-phase peptide synthesis. It features a tert-butyl group that shields the hydroxyl side chain, preventing unwanted side reactions during coupling. This derivative ensures high purity and stability under standard peptide synthesis conditions.

CAS No.: 4378-13-6
Molecular Formula: C₈H₁₇NO₃
Purity: 99% min

Appearance White solid
Molecular Weight 175.23 g/mol
Density 1.1±0.1 g/cm³
Boiling Point 275.3±30.0 °C at 760 mmHg
Melting Point 244–247 °C
Flash Point 120.3±24.6 °C
Packaging 25kg/fibre drum
Storage Conditions Keep in dark place, inert atmosphere, room temperature
Customs Code 29241990
Production capacity 1 ton/month

Product Name
1. O-tert-Butyl-L-threonine;
2. H-Thr(tBu)-OH;
3. (2S,3R)-2-Amino-3-(tert-butoxy)butanoic acid;
4. L-Threonine, O-(1,1-dimethylethyl)-;
5. (2S,3R)-2-amino-3-[(2-methylpropan-2-yl)oxy]butanoic acid;
6. O-t-Butyl-L-threonine;
7. (2S,3R)-2-amino-3-tert-butoxybutanoic acid;
8. O-tert-Butyl-L-allo-threonine;
9. (2S,3R)-2-azaniumyl-3-[(2-methylpropan-2-yl)oxy]butanoate
Applications Raw material for GLP-1 peptide synthesis and polypeptides