H-Ser(tBu)-OH

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H-Ser(tBu)-OH (CAS 18822-58-7) is a protected form of L-Serine, where the hydroxyl group is masked by a tert-butyl ether. This modification prevents side reactions during peptide elongation, making it especially useful in solid-phase peptide synthesis (SPPS) involving GLP-1 analogs and other therapeutic peptides.

CAS No.: 18822-58-7
Molecular Formula: C₇H₁₅NO₃
Purity: 99% min

Appearance White powder
Molecular Weight 161.20 g/mol
Density 1.08 g/cm³
Boiling Point 266.0 ± 30.0 °C at 760 mmHg
Fusing Point -220 °C (decomposition)
Flash Point 114.6 ± 24.6 °C
Packaging 25 kg / fibre drum
Storage Conditions Keep in dark place, inert atmosphere, room temperature
Customs Code 29225090
Production capacity 1.5 tons/month

Product Name
1. H-Ser(tBu)-OH;
2. O-tert-Butyl-L-serine;
3. O-(tert-butyl)-L-serine;
4. L-Serine, O-(1,1-dimethylethyl)-;
5. o-tert-butylserine;
6. (2S)-2-amino-3-[(2-methylpropan-2-yl)oxy]propanoic acid;
7. Serine tert-butyl ether;
8. (2S)-2-azaniumyl-3-[(2-methylpropan-2-yl)oxy]propanoate;
9. (S)-2-Amino-3-(tert-butoxy)propanoic acid
Applications Raw material for GLP-1 peptide synthesis, polypeptides