Pilot Scale Homogenizer

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High Pressure Homogenizer

Designed for process optimization and validation in food & beverage, pharmaceutical, biotechnology and cosmetic industries

The AH-PILOT series is designed for lab-scale and pilot-scale processing in the biopharmaceutical, food, cosmetics, and new materials industries. Powered by a 5.5 kW motor, this homogenizer efficiently handles viscous materials and those containing particulates.

Product Specifications

Models	AH-PILOT	AH-PILOT 16	AH-PILOT 22
Design Pressure (bar)	1800	1500	800
Working Pressure (bar)	0-1500	0-1000	0-600
Min. Volume (ml)	50	50	50
Flow Rate (L/H)	20-40	50-60	100
Power (kW)	5.5	5.5	5.5
Inlet Size (μm)	＜500	＜500	＜500
Inlet Temperature (℃)	＜90	＜9	＜9
Inlet Viscosity (cP)	＜2000	＜2000	＜2000
Weight (kg)	240	240	240
Dimensions (mm)	840635920	840635920	840635920

Features

Suitable for laboratory and pilot-scale applications, with zero material residue
Specialized feeding valve designed for direct feeding without venting
Built-in temperature control systems ensure stable operation
Visual pressure trends and alarm display with a user-friendly interface for easy monitoring
Constructed with 316L stainless steel for durability and stability, extending the homogenizer’s service life
Dual overpressure protection to enhance the homogenizer’s reliability and safety
Equipped with a variable flow control system for adjustable flow rates
Complies with GMP standard and CE certifications
Optional two-stage homogenization and PLC control

Working Principle

The high-pressure pilot-scale homogenizer utilizes a high-pressure reciprocating plunger pump to pressurize the sample and forces it through an adjustable homogenizing valve assembly. The sample is then subjected to intense compression. When passing through the narrow flow-limiting gap in the homogenizing valve, the high velocity and pressure create cavitation, turbulence, and shearing effects that disperse and homogenize aggregated particles.

Related Cases

Nanocellulose preparation
Cell disruption of the freshwater microalgae Haematococcus pluvialis
Chlorella cell disruption using a high-pressure homogenizer

Can the pilot homogenizer bridge the lab-to-pilot transition for the biopharmaceutical industry?

Yes. ATS’s high-pressure pilot-scale homogenizers have a minimum volume of 50 ml, making them suitable for laboratory-scale processing, and a capacity of 100 L/H that satisfies pilot-scale processing requirements. The homogenizers are also GMP-compliant and CE-certified, meeting the transition needs of the biopharmaceutical industry.

Does the pilot-scale homogenizer support additional upgrades for improved homogenization needs?

Yes. The pilot-scale high-pressure homogenizer supports additional upgrades of two-stage homogenization and PLC control system.

Can the pilot-scale homogenizer process viscous materials with granules while meeting flow rate requirements?

Yes. The pilot-scale high-pressure homogenizer is equipped with a 5.5kW motor and can handle materials with viscosity <2000cP and particle size <500μm. And the flow rate ranges from 20 to 100 L/H, suitable for laboratory and pilot-scale production needs.

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